Dernière modification par Rhys (15 novembre 2018 à 18:33)
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Contraindications
Known or suspected pregnancy is a contraindication of levonorgestrel as an emergency contraceptive.[29]
Side effects
See also: Progestin § Side effects
After intake of 1.5 mg levonorgestrel in clinical trials, very common side effects (reported by 10% or more) included: hives, dizziness, headache, nausea, abdominal pain, uterine pain, delayed menstruation, heavy menstruation, uterine bleeding, and fatigue; common side effects (reported by 1% to 10%) included diarrhea, vomiting, and painful menstruation; these side effects usually disappeared within 48 hours.[30][31]
Overdose
Overdose of levonorgestrel as an emergency contraceptive has not been described.[29] Nausea and vomiting might be expected.[29]
Interactions
If taken together with drugs that induce the CYP3A4 cytochrome P450 liver enzyme, levonorgestrel may be metabolized faster and may have lower effectiveness.[32]
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